اثر هشت هفته تمرین مقاومتی بر سطوح سرمی FGF21 ، لسیتین کلسترول آسیل ترانسفراز و نسبت LDL-C به HDL-Cدر زنان چاق

نوع مقاله: مقاله پژوهشی

نویسندگان

گروه فیزیولوژی ورزشی، واحد آیت ا... آملی، دانشگاه آزاد اسلامی، آمل

چکیده

مقدمه و هدف: فاکتور رشد فیبروبلاست 21 (FGF 21) پروتئینی است که در مصرف گلوکز، متابولیسم چربی و تعادل انرژی نقش دارد. هدف از مطالعه حاضربررسی تاثیر 8 هفته تمرین مقاومتی بر تغییرات سرمی FGF21، لسیتین کلسترول آسیل ترانسفراز و نسبت LDL-C به HDL-C در زنان چاق بود.
مواد و روش­ها: 20 زن چاق (سن27/2±35/30 سال، قد 05/0±61/1 متر، وزن 69/5±24/85 کیلوگرم، شاخص توده بدنی 40/1±49/32 کیلوگرم بر متر مربع) به طور تصادفی به 2 گروه تمرین مقاومتی و کنترل تقسیم شدند. فعالیت مقاومتی شامل 6 ایستگاه با شدت 50-75 درصد یک تکرار بیشینه، سه روز در هفته و به مدت 8 هفته بود. نمونه گیری خون در دو مرحله قبل و بعد از 8  هفته (48 ساعت پس از آخرین جلسه تمرینی) بعد از 12 ساعت ناشتایی گرفته شد. از آزمون آنالیز واریانس در اندازه گیری مکرر جهت تجزیه و تحلیل داده ها استفاده شد.
یافته ها: نتایج تحقیق نشان داد که سطوح سرمی FGF21و لسیتین کلسترول آسیل ترانسفرازدر گروه تمرین بعد از 8 هفته تمرین مقاومتی در مقایسه با گروه کنترل افزایش معناداری پیدا کرد( p بحث و نتیجه گیری: نتایج تحقیق حاضر نشان داد که هشت هفته تمرینات مقاومتی احتمالاً از طریق افزایش سطح FGF21 و لسیتین کلسترول آسیل ترانسفراز می تواند. موجب بهبود پروفایل لیپید در افراد چاق شده و به عنوان یک فاکتور ضد آتروژنیک از بروز بیماریهای قلبی عروقی در افراد چاق جلوگیری کند.

تازه های تحقیق

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کلیدواژه‌ها


عنوان مقاله [English]

The effects of eight weeks of resistance training on serum levels of FGF21, LCAT and LDL-C to HDL-C ratio in obese women

نویسندگان [English]

  • Asiyeh abbasi-daloii
  • . .
  • Ahmad Abdi
  • Mohammad Ghasemi
.
چکیده [English]

Background&Purpose: fibroblast growth factor 21 (FGF 21) protein involved in glucose, lipid metabolism and energy balance. The aim of this study was to determine effect of 8 weeks of resistance training on FGF21, LCAT, and LDL-C to HDL-C ratio in obese women.
Material and methods: 20 obese women (Age 30/35 ± 2/27 years, height 1/61 ± 0/05 m, weight 85/24 ± 5/69 kg, BMI 32/49 ± 1/4 kg/m2; mean ± SD ) were randomly divided into 2 groups: resistance training and control groups. Resistance exercise include 6 stations with the intensity of 50-75% of 1RM, three days a week for 8 weeks. Blood samples were collected before and after 8 weeks (48 hours after the last training session) after 12 hours fasting. Analysis of variance for repeated measures was used to analyze the data.
Results: The results showed that FGF21 and LCAT significantly increased in training group compared to the control group during the 8 weeks of resistance training(Respectively p =0.037 and p =0.009). Also LDL-C to HDL-C was significantly reduced ratio during 8 weeks of resistance activity compared with the control group(p =0.004).
Conclusion: The results of this study showed that eight weeks of resistance training, probably through increased levels of FGF21 and  LCAT can be and as anti-atherogenic factor prevented cardiovascular diseases in obese people.

کلیدواژه‌ها [English]

  • Resistance Training
  • FGF21
  • LDL-C to HDL-C ratio
  • obese women

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