پاسخ فاکتور نوروترفیک مغزی عضلات نعلی و خم کننده بلند شست موش های صحرایی به یک جلسه فعالیت مقاومتی

نوع مقاله: مقاله پژوهشی

نویسندگان

1 دانشجوی دکتری فیزیولوژی ورزش

2 دانشیار دانشگاه تربیت مدرس

3 کارشناش ارشد فیزیولوژی ورزش دانشگاه تربیت مدرس

4 استادیار دانشگاه علامه طباطبایی

چکیده

سابقه و هدف: اخیرا تاثیر فعالیت بدنی بر عملکرد نوروتروفینها از جمله فاکتور نروترفیک مغزی (BDNF) و نقش آن در عضله مورد توجه قرار گرفته است. لذا در تحقیق حاضر پاسخ BDNF به یک جلسه فعالیت مقاومتی در عضلات نعلی و خم­کننده بلند شست (FHL) موش­های صحرایی مورد بررسی قرار گرفت.
روش­شناسی: تعداد 24 سر موش صحرایی نر به طور تصادفی به 2 گروه کنترل و تمرین تقسیم شدند. در جلسه تمرین حیوانات با وزنه هایی برابر با 30% وزنشان از نردبان بالا رفتند. سپس24 و 48 ساعت بعد از جلسه تمرین بیهوش شده و بلافاصله عضلات خارج شدند.
یافته­ها: نتایج نشان داد که مقدار پایه پروتئین  BDNFدر عضله خم کننده بلند شست بیشتر از عضله نعلی بود. همچنین مقدار این پروتئین در عضله­ی FHL، سطوح پایین­تری از معنی­داری را در دو نقطه زمانی 24 و 48 ساعت بعد از تمرین نشان داد، در حالی که در عضله نعلی تغییرات معنی­داری مشاهده نشد.
نتیجه­گیری: تفاوت در مقادیر پایه پروتئین  BDNFدر عضلات FHL و نعلی، کاهش معنی­دار این پروتئین در عضله  FHLو عدم تغییر این پروتئین در عضله نعلی به دنبال فعالیت مقاومتی، دلایلی بر تاثیرات ویژه پروتئین  BDNFدر هر یک از عضلات تند و کند انقباض است.
 

کلیدواژه‌ها


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