پاسخ آپلین و امتیاز کلی خطر متابولیک در زنان میان‌سال دارای سندرم متابولیک به تمرین هوازی

نوع مقاله: مقاله پژوهشی

نویسندگان

1 استادیار فیزیولوژی ورزشی، گروه علوم ورزشی، دانشکده علوم تربیتی و روانشناسی، دانشگاه شهید مدنی آذربایجان، تبریز، ایران

2 استادیار فیزیولوژی ورزشی، پژوهشگاه تربیت بدنی و علوم ورزشی، تهران، ایران

چکیده

سابقه و هدف: آپلین در بیماری‌های متابولیک افزایش می‌یابد و سطوح آن می‌تواند به عنوان یک شاخص ویژه برای حساسیت انسولینی و همچنین علت شناسی آن به کار رود. هدف از پژوهش حاضر بررسی تأثیر هشت هفته تمرین هوازی بر سطوح آپلین سرمی و شاخص‌های خطر متابولیک در زنان دارای سندرم متابولیک بود.
مواد و روش­ها: 24 زن دارای سندرم متابولیک به‌طور تصادفی به دو گروه تمرین هوازی (12 نفر) و کنترل (12 نفر) تقسیم شدند. گروه تمرین هوازی به مدت 8 هفته، 3 جلسه در هفته با شدت 50-60 درصد ضربان قلب ذخیره به مدت 20-40 دقیقه به اجرای تمرینات هوازی پرداختند. قبل و 48 ساعت پس از آخرین جلسه تمرین اندازه‌گیری‌های ترکیب‌بدنی و خون‌گیری انجام‌شد. برای مقایسه درون گروهی میانگین­ها از آزمون t همبسته، برای مقایسه بین گروهی تغییرات نیز از آزمون t مستقل و برای بررسی همبستگی بین متغیرها از آزمون پیرسون استفاده شد.
یافته‌ها: بین مقدار آپلین پایه کل آزمودنی‌ها در پیش‌آزمون و کلیه شاخص‌های خطر متابولیک همبستگی معنی‌داری مشاهده شد (05/0p نتیجه‌گیری: تمرین هوازی می‌تواند باعث کاهش آپلین سرم و بهبود مقاومت انسولینی و برخی شاخص‌های خطر متابولیک در زنان دارای سندرم متابولیک شود. اما کاهش آپلین همراه با بهبود وضعیت متابولیکی، از نقش آپلین به عنوان یک عنصر واسطه‌ای احتمالی در بروز آثار تمرین بدنی بر نارسایی‌های متابولیک دلالت می‌کند.

کلیدواژه‌ها


عنوان مقاله [English]

The Response of Apelin and overall metabolic risk to Aerobic Training in Middle-aged Female patients with Metabolic Syndrome

نویسندگان [English]

  • Karim Azali Alamdari 1
  • Hadi Rohani 2
1 Sport Sciences Department, Faculty of Psychology and Education, Azarbaijan Shahid Madani University, Tabriz, Iran
2 Sport Sciences Research Institute of Iran, Tehran, Iran
چکیده [English]

Background & Purpose: Circulatory Apelin increases in metabolic disorders and its levels could be used as a specific index for insulin sensitivity and its etiology. The aim of this study was to investigate the effects of eight weeks aerobic training on serum Apelin and metabolic risk factors in women with metabolic syndrome.
Methodology: 24 women with metabolic syndrome were randomly assigned into exercise (n=12) or control (n=12) groups. Subjects in exercise group carried out 20-40 min aerobic exercise program at 50-60% of heart rate reserve 3 sessions per week for 8 weeks. Body composition was assessed and blood samples were taken prior to the training program and 48 h after the last training session. Paired t-test was used for within-group comparison and independent t-test was used for between-group comparison, and Pearson's correlation test was used to evaluate the relationship between variables.
Results: Significant correlations were observed between Apelin levels and all the metabolic risk factors at the baseline where all subjects included in the analysis (p0.05). Body weight, Apelin, glucose, insulin resistance index, mean atrial pressure and waist circumference were significantly decreased (p
Conclusions: Aerobic training can reduce serum Apelin levels and improve insulin resistance and also some of the metabolic risk factors in women with metabolic syndrome. However, the decreased Apelin levels in accompany with an improved metabolic profile indicates on its mediatory role to induce metabolic improvements by physical exercise.

کلیدواژه‌ها [English]

  • Aerobic training
  • Apelin
  • Insulin Resistance
  • Lipid Profile
  • Metabolic Syndrome

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