نوع مقاله : مقاله پژوهشی
نویسندگان
1 دانشجوی دکتری فیزیولوژی ورزشی، دانشکده علوم ورزشی، دانشگاه مازندران، بابلسر، ایران.
2 استاد گروه فیزیولوژی ورزشی، دانشکده علوم ورزشی، دانشگاه مازندران، بابلسر، ایران. قطب علمی پایش سلامت ورزشی و پویش قهرمانی دانشگاه مازندران
3 استادیار گروه فیزیولوژی ورزشی، دانشکده علوم ورزشی، دانشگاه مازندران، بابلسر، ایران.
چکیده
کلیدواژهها
عنوان مقاله [English]
نویسندگان [English]
Objectives: The liver is affected by various factors in energy metabolism, including peroxisome proliferator-activated receptors (PPARs). The aim of the present study was to investigate the effects of high-intensity interval and resistance training on the expression of PPAR-α, PPAR-β/δ, and PPAR-γ in the liver tissue of male Wistar rats.
Methods: Fifteen male Wistar rats (250 ± 25 g) and 8 weeks of age were divided into three groups: resistance training, high-intensity interval training, and control. The resistance training group performed 3 sessions per week for 8 weeks using a 1-meter ladder with 26 steps and an intensity of 50 to 100% of maximum weight-bearing capacity. The high-intensity interval training group performed high-intensity running (six 4-minute periods at an intensity of 85 to 95% of maximum oxygen consumption, with 3 minutes of active recovery between each period at an intensity of 40 to 50% of maximum oxygen consumption on a treadmill) for 8 weeks and 5 sessions per week. The expression of PPAR-α, PPAR-β/δ, and PPAR-γ genes was measured in liver tissue by Real Time PCR. The findings were analyzed by one-way analysis of variance.
Results: Analysis of variance test showed that the mean expression levels of any of the genes PPAR-α (P=0.7), PPAR-γ (P=0.5) and PPAR-β/δ (P=0.3) in the liver tissue of rat in the three groups of control, resistance training and intense interval training were not significantly different from each other.
Conclusion: The results of this study showed that eight weeks of intense resistance and interval training did not have a significant effect on the expression of PPAR-α, PPAR-β/δ, and PPAR-γ genes in liver tissue, which emphasizes the complexity of regulating energy metabolism in the liver.
کلیدواژهها [English]