عنوان مقاله [English]
Coronavirus disease (COVID-19) is a public world crisis. The host's immune response to the virus depends on factors such as genetics, age, physical condition and its main receptor angiotensin-converting enzyme 2). As is generally the elderly, obese and type 2 diabetes with severe conditions encountered. On the other hand, exercise training modulates the immune system. During and after exercise, pro-inflammatory and anti-inflammatory cytokines are released and circulating lymphocytes increases. Exercise training reduces the incidence of disease, the severity of symptoms and mortality from viral infections. In this narrative review study, related articles from all databases including PubMed, ISI, Scopus and Google scholar were examined. Also, in the article search process, the keywords of Coronavirus, Covid-19, moderate-intensity exercise training, high-intensity exercise training and immune system were used. Various studies have reported suppression of the interferon type 1(IFN-I) response in COVID-19. In the severe disease conditions, storms of pro-inflammatory cytokines and lymphopenia occur. On the other hand, exercise training with moderate intensity strengthens the immune system and helps prevent infectious viral diseases. But high-intensity exercise training can have negative effects on the immune system, which reduces the function of the immune system and increases the risk of infectious diseases. Therefore, regular moderate-intensity exercise is considered as an aid tool for strengthening the immune system for coronavirus. More studies are needed on the role of exercise training on the immune system to against the coronavirus.