نوع مقاله : مقاله پژوهشی
نویسندگان
1 دانشجوی دکتری فیزیولوژی ورزشی دانشگاه تهران
2 مرکز تحقیقات غدد و متابولیسم بیمارستان شریعتی
3 دانشیاردانشکده تربیت بدنی وعلوم ورزشی دانشگاه تهران
4 دانشیار دانشکده تربیت بدنی وعلوم ورزشی دانشگاه تهران
چکیده
کلیدواژهها
عنوان مقاله [English]
نویسندگان [English]
Production of the reactive oxidative species (ROS) as free radicals resaults in oxidative stress and therefore cell structural damage following the exercise. This study aimed to investigate the effect of a single endurance exercise session on the lipid peroxidation biomarker, malondealdehyde (MDA) and serum total antioxidant capacity (TAC) in wistar rats. Thus 14 wistar rats aged 4 month were assigned randomly into one of 2 groups: rest (n=7), and endurance exercise (n=7). All groups were subjected a familiarization treadmill protocol for two weeks that started with walking and progress to the running speed 10 m/min. Finally, rats in endurance exercise group exercised at 70%vo2max. The running speed were 25 m/min at a gradient 5% in endurance group. Blood samples taken following the exercise from rested and exercised groups. Serum total antioxidant capacity (TAC) and serum malondealdehyde (MDA), were measured. Results showed: The MDA increased significantly following endurance exercise in the endurance group compare to the rest group (p</01). The TAC increased significantly following endurance exercise in the endurance group compare to the rest group (p</05).