بررسی اثر 12 هفته تمرین عملکردی شدید و مصرف گیاه چرخه بر شاخص‌های گلیسمی و آنزیم‌های آنتی‌اکسیدانی زنان مبتلا به دیابت نوع 2

نوع مقاله : مقاله پژوهشی

نویسندگان

1 کارشناس ارشد فیزیولوژی ورزشی، دانشکده علوم تربیتی و روانشناسی، دانشگاه محقق اردبیلی، اردبیل، ایران.

2 استاد فیزیولوژی ورزشی، دانشکده علوم تربیتی و روانشناسی، دانشگاه محقق اردبیلی، اردبیل، ایران.

3 دانشیار فیزیولوژی ورزشی، دانشکده علوم تربیتی و روانشناسی، دانشگاه محقق اردبیلی، اردبیل، ایران.

10.22080/jaep.2026.30489.2239

چکیده

اهداف: افزایش رادیکال‌های آزاد و فشار اکسایشی یکی از عوارض بیماری دیابت نوع دوم می‌باشد. هدف پژوهش حاضر بررسی اثر 12 هفته تمرین عملکردی شدید و مصرف گیاه چرخه بر شاخص‌های گلیسمی و آنزیم‌های آنتی‌اکسیدانی زنان مبتلا به دیابت نوع 2 بود.
روش مطالعه: چهل زن دیابتی به‌صورت تصادفی در 4 گروه مکمل، تمرین، تمرین- مکمل و کنترل قرار گرفتند. در جلسه پیش‌آزمون نمونه خونی برای اندازه‌گیری مالون‌دی‌آلدئید، گلوتاتیون پراکسیداز، سوپر اکسید دیسموتاز و شاخص‌های گلیسمی گرفته شد. دو گروه تمرین- مکمل و تمرین به مدت 12 هفته، هر هفته 3 جلسه، هر جلسه به مدت 60 دقیقه تمرینات عملکردی شدید را انجام دادند. گروه‌های مکمل هم‌زمان با انجام تمرینات، گیاه چرخه را مصرف نمودند.
یافته­ ها: سطوح گلوکز خون ناشتا، هموگلوبین A1c‌ و مالون‌دی‌آلدئید سرمی در هر 3 گروه تمرین- مکمل، تمرین و مکمل کاهش معنی‌داری داشت (001/0 =p  ). سطح گلوکز خون در گروه تمرین- مکمل در مرحله پس‌آزمون نسبت به سه گروه دیگر بطور معنی‌داری پایین‌تر بود (05/0p ≤ ) ولی سطح هموگلوبین A1c تنها نسبت به گروه مکمل و کنترل بطور معنی‌داری پایین‌تر بود (05/0p ≤ ). سطوح انسولین، گلوتاتیون پراکسیداز، سوپر اکسید دیسموتاز و ظرفیت آنتی‌اکسیدانی در گروه تمرین- مکمل، تمرین و مکمل افزایش معنی‌داری داشت (001/0 =p  در هر سه گروه و برای هر 4 متغیر). سطوح گلوتاتیون پراکسیداز و سوپر اکسید دیسموتاز در گروه تمرین- مکمل در مرحله پس‌آزمون نسبت به سه گروه دیگر بطور معنی‌داری بالاتر بود (05/0p ≤ ).
نتیجه‌گیری: هم تمرینات عملکردی شدید و هم مصرف چرخه موجب بهبود وضعیت آنتی‌اکسیدانی و شاخص‌های گلیسمی زنان مبتلا به دیابت نوع 2 می‌گردد. اثر ترکیبی تمرین عملکردی و مصرف گیاه چرخه در بهبود وضعیت آنتی‌اکسیدانی و شاخص‌های گلیسمی در مقایسه با هر یک از این متغیرها به‌تنهایی بیشتر است.

کلیدواژه‌ها


عنوان مقاله [English]

The Effect of 12 Weeks High Intensity Fictional Training and Consumption of Launaea Acanthodes on Glycemic Indices and Antioxidant Enzymes in Women with Type 2 Diabetes

نویسندگان [English]

  • Shadi Fathi 1
  • Roghayyeh Afroundeh 2
  • Ameneh Pourrahim 3
1 Department of Exercise Physiology, Faculty of Educational Sciences and Psychology, University of Mohaghegh Ardabili, Ardabil, Iran.
2 Department of Exercise Physiology, Faculty of Educational Sciences and Psychology, University of Mohaghegh Ardabili, Ardabil, Iran.
3 Department of Exercise Physiology, Faculty of Educational Sciences and Psychology, University of Mohaghegh Ardabili, Ardabil, Iran.
چکیده [English]

Objectives: An increase in free radicals and oxidative stress is one of the complications of type 2 diabetes. The aim of the present research was to investigate the effect of 12 weeks of High Intensity Functional training (HIFT) and the consumption of Launaea Acanthodes on glycemic indices and antioxidant enzymes in women with type 2 diabetes. 
Methods: Forty type 2 diabetic women were randomly divided into 4 groups: supplement, training, training + supplement and control. Training groups performed HIFT for 12 weeks, 3 sessions per week, and each session 60 minutes. Supplement groups consumed the Launaea acanthodes at the same time as doing the exercises. Serum levels of malondialdehyde, glutathione peroxidase, superoxide dismutase and glycemic indices were measured.
 
Results: The level of Fasting blood glucose, hemoglobin A1C and malondialdehyde were significantly reduced in the exercise-supplement, exercise and supplement groups (p=0.001 in all three groups). The blood glucose level in the exercise-supplement group was significantly lower than the other three groups in the post-test phase (p<0.05), but the hemoglobin A1C level was only significantly lower than the supplement and control group (p<0.05). The level of insulin, glutathione peroxidase, superoxide dismutase and antioxidant capacity increased significantly in the exercise-supplement, exercise and supplement groups (p=0.001 in all three groups and for all 4 variables). The level of glutathione peroxidase and superoxide dismutase were significantly higher in the exercise-supplement group than the other three groups in the post-test phase (p<0.05).
Conclusion: Both HIFT exercises and the consumption of Launaea acanthodes improved the antioxidant status and glycemic indices of women with type 2 diabetes. The improvement was greater when the two are combined compared to either of them alone.

کلیدواژه‌ها [English]

  • High Intensity Functional Activity
  • Launaea Acanthodes
  • Glycemic Indices
  • Antioxidant Enzymes
  • Type 2 Diabetes
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