نوع مقاله : مقاله پژوهشی
نویسندگان
1 دانشجوی دکتری فیزیولوژی ورزش، گروه فیزیولوژی ورزش، دانشکده ادبیات و علوم انسانی، واحد کرمانشاه، دانشگاه آزاد اسلامی، کرمانشاه، ایران
2 استادیارگروه فیزیولوژی ورزش، دانشکده ادبیات و علوم انسانی، واحد کرمانشاه، دانشگاه آزاد اسلامی، کرمانشاه، ایران
3 استادیار گروه فیزیولوژی ورزشی، واحد کنگاور، دانشگاه آزاد اسلامی، کنگاور، ایران
4 استادیار گروه فیزیولوژی ورزشی، واحد اسلام آبادغرب، دانشگاه آزاد اسلامی، اسلام‌آباد غرب، ایران
5 دانشیار گروه دامپزشکی، دانشکده علوم پزشکی، واحد کرمانشاه، دانشگاه آزاد اسلامی، کرمانشاه، ایران
چکیده
کلیدواژه‌ها
عنوان مقاله [English]
نویسندگان [English]
Objectives: The aim of the present study was to determine the effect of eight weeks of endurance, resistance and combined exercise training on plasma levels of adipolin and furin in obese diabetic old rats.
Methods: 32 obese rats were randomly divided into 4 groups (endurance training, resistance training, combined training and control). Rats were made diabetic by intraperitoneal injection of streptozotocin at a dose of 55 mg/kg body weight. Endurance training was performed on a treadmill at a moderate intensity (50-70% of maximum running capacity) for 1 hour per day, and resistance training was performed at an intensity of 50-70% of maximum load, with 15 climbs per session and a 1-minute interval between climbs. Combined training was also performed as a combination of endurance and resistance training, one day on the treadmill and one day on the ladder. 48 hours after the end of the training, plasma levels of adipolin and furin were measured by ELISA. Data analysis was performed using one-way ANOVA and Tukey's post hoc test.
Results: The results showed that serum adiponectin levels were significantly increased in the endurance training (P=0.001), resistance training (mean P=0.003) and combined training (P=0.001) groups compared to the control group. Also, the level of this adipokine was significantly higher in the endurance training group compared to the resistance training (P=0.023). Serum furin levels were significantly lower in the endurance training, resistance training and combined training groups (P=0.001) than in the control group.
Conclusion: The results of the study showed that eight weeks of endurance, resistance and combined training can have positive effects on changes in adiponectin and furin. However, these changes for adiponectin depend to some extent on the type of exercise.
کلیدواژه‌ها [English]
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