نوع مقاله : مقاله پژوهشی
نویسندگان
1 کارشناسی ارشد، گروه فیزیولوژی ورزشی، دانشکده علوم ورزشی، دانشگاه گیلان، رشت ایران،
2 دانشگاه گیلان-دانشکده علوم ورزشی- گروه فیزیولوژی ورزش
3 استاد، متخصص مغز و اعصاب، استاد دانشگاه علوم پزشکی، دانشگاه علوم پزشکی گیلان، رشت، ایران
چکیده
کلیدواژه‌ها
عنوان مقاله [English]
نویسندگان [English]
Objectives: Multiple sclerosis is a progressive and demyelinating disease that can cause cognitive disorders such as anxiety and depression by changing the levels of hormones of the hypothalamus-pituitary-adrenal axis. Therefore, the aim of this study was the effect of 8 weeks of aerobic exercise on the serum concentration of cortisol, dopamine, anxiety and depression in women with MS.
Methods: 26 female patients with relapsing-remitting MS with an EDSS score between 0 and 5.5 who referred to the neurology clinic of Rasht University of Medical Sciences were divided into two aerobic exercise groups and a control group. The levels of depression and anxiety were assessed with Beck's 21-question questionnaire. During eight weeks, aerobic training started from two days a week and reached three days a week at the end of the course. Also, serum cortisol and dopamine levels were evaluated before and after the training period. The data was analyzed using covariance statistical method at the level of p<0.05.
Results: Studies show that the levels of cortisol (P=0.601), dopamine (P=0.815) and anxiety (P=0.275) did not change significantly during eight weeks of aerobic exercise, but depression levels improved during this period (P=0.001).
Conclusion: Based on the results of the present study, 8 weeks of aerobic exercise improves depression in MS patients, but it has no effect on anxiety and the level of physiological indicators, including the serum concentration of dopamine and cortisol.
کلیدواژه‌ها [English]
)