##
Mulya A,
Kirwan JP. Brown and beige adipose tissue: Therapy for obesity and its comorbidities?
Endocrinol Metab Clin North Am. 2016; 45(3): 605-21.##
Hill JO,
Wyatt HR,
Peters JC. Energy balance and obesity.
Circulation. 2012; 126(1): 126-32.##
Stanford KI,
Goodyear LJ. Exercise regulation of adipose tissue.
Adipocyte. 2016; 5(2): 153-62.##Stanford KI, Middelbeek RJ, Goodyear LJ.
exercise effects on white adipose tissue: beiging and metabolic adaptations. Diabetes. 2015; 64(7): 2361-8.##
Wu J,
Boström P,
Sparks LM,
Ye L,
Choi JH,
Giang AH, et al. Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human.
Cell. 2012; 150(2): 366-76.##
Stanford KI,
Middelbeek RJ,
Townsend KL,
Lee MY,
Takahashi H,
So K, et al. A novel role for subcutaneous adipose tissue in exercise-induced improvements in glucose homeostasis.
Diabetes. 2015; 64(6): 2002-14.##
Sutherland LN,
Bomhof MR,
Capozzi LC,
Basaraba SA,
Wright DC. Exercise and adrenaline increase PGC-1{alpha} mRNA expression in rat adipose tissue.
J Physiol. 2009; 587(Pt 7): 1607-17.##
Trevellin E,
Scorzeto M,
Olivieri M,
Granzotto M,
Valerio A,
Tedesco L, et al. Exercise training induces mitochondrial biogenesis and glucose uptake in subcutaneous adipose tissue through eNOS-dependent mechanisms.
Diabetes. 2014; 63(8): 2800-11.##
Boström P,
Wu J,
Jedrychowski MP,
Korde A,
Ye L,
Lo JC, et al. A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis.
Nature. 2012; 481(7382): 463-8.##
Cao L,
Choi EY,
Liu X,
Martin A,
Wang C,
Xu X, et al. White to brown fat phenotypic switch induced by genetic and environmental activation of a hypothalamic-adipocyte axis.
Cell Metab. 2011; 14(3): 324-38.##
Xu X,
Ying Z,
Cai M,
Xu Z,
Li Y,
Jiang SY, et al. Exercise ameliorates high-fat diet-induced metabolic and vascular dysfunction, and increases adipocyte progenitor cell population in brown adipose tissue.
Am J Physiol Regul Integr Comp Physiol. 2011; 300(5): R1115-25.##Pedersen BK, Febbraio MA.
Muscles, exercise and obesity: skeletal muscle as a secretory organ. Nat Rev Endocrinol. 2012; 8(8): 457-65.##
Rao RR,
Long JZ,
White JP,
Svensson KJ,
Lou J,
Lokurkar I, et al. Meteorin-like is a hormone that regulates immune-adipose interactions to increase beige fat thermogenesis.
Cell. 2014; 157(6): 1279-91.##Li ZY, Zheng SL, Wang P, Xu TY, Guan YF, Zhang YJ et al. Subfatin is a novel adipokine and unlike Meteorin in adipose and brain expression. CNS neuroscience & therapeutics 2014; 20(4): 344-54.##
Li ZY,
Song J,
Zheng SL,
Fan MB,
Guan YF,
Qu Y, et al. Adipocyte Metrnl Antagonizes Insulin Resistance Through PPARγ Signaling.
Diabetes. 2015; 64(12): 4011-22.##
Eaton M,
Granata C,
Barry J,
Safdar A,
Bishop D,
Little J.P. Impact of a single bout of high-intensity interval exercise and short-term interval training on interleukin-6, FNDC5, and Metrnl mRNA expression in human skeletal muscle, JSHS. 2018; 7: 191-196.##Craig BW, Hammons GT, Garthwaite SM, Jarett L & Holloszy JO. Adaptation of fat cells to exercise: response of glucose uptake and oxidation to insulin. J. Appl. Physiol. Respir. Environ. Exercise. Physiology. 51, 1500–1506 (1981).##Sharma N, Castorena CM, Cartee GD. Greater insulin sensitivity in calorie restricted rats occurs with unaltered circulating levels of several important myokines and cytokines. Nutrition Metabolism (Lond) 2012; 9: 90-4.##Shaw K, Gennat H, O'Rourke P, Del Mar C. Exercise for Overweight or Obesity. Cochrane Database Syst Rev. 2006; 18: CD003817.##Dwyer GB, Davis SE. ACSM's health-related physical fitness assessment manual. Lippincott Williams & Wilkins. 2008.##
Glaister M,
Hauck H,
Abraham CS,
Merry KL,
Beaver D,
Woods B, et al. Familiarization, reliability, and comparability of a 40-m maximal shuttle run test.
J Sports Sci Med. 2009; 8(1): 77-82.##Wallace TM, Levy JC, Matthews DR. Use and abuse of HOMA modeling. Diabetes Care.2004; 27: 1487–1495.##
Kelly DP. Medicine. Irisin, light my fire.
Science. 2012; 336(6077): 42-3.##
Macpherson RE,
Hazell TJ,
Olver TD,
Paterson DH,
Lemon PW. Run sprint interval training improves aerobic performance but not maximal cardiac output.
Med Sci Sports Exerc. 2011; 43(1): 115-22.##
Talanian JL,
Galloway SD,
Heigenhauser GJ,
Bonen A,
Spriet LL. Two weeks of high-intensity aerobic interval training increases the capacity for fat oxidation during exercise in women.
J Appl Physiol (1985). 2007; 102(4): 1439-47.##
Tjønna AE,
Stølen TO,
Bye A,
Volden M,
Slørdahl SA,
Odegård R, et al. Aerobic interval training reduces cardiovascular risk factors more than a multitreatment approach in overweight adolescents.
Clin Sci (Lond). 2009; 116(4): 317-26.##
Trapp EG,
Chisholm DJ,
Freund J,
Boutcher SH. The effects of high-intensity intermittent exercise training on fat loss and fasting insulin levels of young women.
Int J Obes (Lond). 2008; 32(4): 684-91.##
Whyte LJ,
Gill JM,
Cathcart AJ. Effect of 2 weeks of sprint interval training on health-related outcomes in sedentary overweight/obese men.
Metabolism. 2010; 59(10): 1421-8.##
Laursen PB,
Blanchard MA,
Jenkins DG. Acute high-intensity interval training improves Tvent and peak power output in highly trained males.
Can J Appl Physiol. 2002; 27(4): 336-48.##
Batacan RB Jr,
Duncan MJ,
Dalbo VJ,
Tucker PS,
Fenning AS. Effects of high-intensity interval training on cardiometabolic health: a systematic review and meta-analysis of intervention studies.
Br J Sports Med. 2017; 51(6):494-503.##
LaForgia J,
Withers RT,
Gore CJ. Effects of exercise intensity and duration on the excess post-exercise oxygen consumption.
J Sports Sci. 2006; 24(12): 1247-64.##
Boutcher SH. High-intensity intermittent exercise and fat loss.
J Obes. 2011; 2011: 868305. ##
Boer PH,
Meeus M,
Terblanche E,
Rombaut L,
Wandele ID,
Hermans L, et al. The influence of sprint interval training on body composition, physical and metabolic fitness in adolescents and young adults with intellectual disability: a randomized controlled trial.
Clin Rehabil. 2014; 28(3): 221-31.##Horowitz JF, Klein S.
Lipid metabolism during endurance exercise. Am J Clin Nutr. 2000; 72(2 Suppl): 558S-63. ##
Freese EC,
Gist NH,
Acitelli RM,
McConnell WJ,
Beck CD,
Hausman DB, et al. Acute and chronic effects of sprint interval exercise on postprandial lipemia in women at-risk for the metabolic syndrome.
J Appl Physiol (1985). 2015; 118(7): 872-9.##
Little JP,
Gillen JB,
Percival ME,
Safdar A,
Tarnopolsky MA,
Punthakee Z, et al. Low-volume high-intensity interval training reduces hyperglycemia and increases muscle mitochondrial capacity in patients with type 2 diabetes.
J Appl Physiol (1985). 2011; 111(6): 1554-60.##
Moholdt TT,
Amundsen BH,
Rustad LA,
Wahba A,
Løvø KT,
Gullikstad LR, et al. Aerobic interval training versus continuous moderate exercise after coronary artery bypass surgery: a randomized study of cardiovascular effects and quality of life.
Am Heart J. 2009; 158(6): 1031-7.##
Jakeman J,
Adamson S,
Babraj J. Extremely short duration high-intensity training substantially improves endurance performance in triathletes.
Appl Physiol Nutr Metab. 2012; 37(5): 976-81.##
Gibala MJ,
McGee SL,
Garnham AP,
Howlett KF,
Snow RJ,
Hargreaves M. Brief intense interval exercise activates AMPK and p38 MAPK signaling and increases the expression of PGC-1alpha in human skeletal muscle.
J Appl Physiol (1985). 2009; 106(3):929-34.##
Towler MC,
Hardie DG. AMP-activated protein kinase in metabolic control and insulin signaling.
Circ Res. 2007; 100(3): 328-41.##
Löffler D,
Landgraf K,
Rockstroh D,
Schwartze JT,
Dunzendorfer H,
Kiess W, et al. METRNL decreases during adipogenesis and inhibits adipocyte differentiation leading to adipocyte hypertrophy in humans.
Int J Obes (Lond). 2017; 41(1): 112-119.##