##White LJ, Castellano V. 2008. Exercise and Brain Health Implications for Multiple Sclerosis Part Neuronal Growth Factors. Journal of sport Medicine. 15(2): 91-100.##lesley j. 2004. exercise and multiple sclerosis. Journal of sport Medicine.11(5): 1100-1077.##Lewis P, Merritt D. 2005. Neurology. New York: ippincott-Williams& Wilkins.##David A. 2004. Multiple Sclerosis. Journal of Clinical Investigation. 2(1): 778-794.##Stachowiak J. 2008. Multiple Sclerosis Types-Types of MS. National Multiple Sclerosis Society. 5(3): 17-28.## Oger J, Al-Araji A, Cabrera-Gomez JA, Clerico M, Contessa G, Durelli L, Giordano L, Herndon RM, Kira JI, Lee MA, McDonnell GV, Palace J, Schapiro RT, Singhal BS. 2007. Multiple sclerosis for the practicing neurologist. New York: Munsat,T-L.22-50.## Gillson G, Wright J, Delack E, Ballasiotes G. 2000. Transdermal Histamine in Multiple Sclerosis, Part Tow: Aproposed Theoretical Basis for Its Use. Alternation Medicine Review. 21(5): 224-248.## Larlori C, Gambi D. 2008. Reduction of free radicals in multiple sclerosis: effect of glatiramer acetate. Multiple Sclerosis. 13(6): 739-748.## Rozenfeld C. 2005. Toxoplasma gondii Prevents Neuron Degeneration by Interferon-γ Activated Microglia in a Mechanism Involving Inhibition of Inducible Nitric Oxide Synthase and Transforming Growth Factor-ß1 Production by Infected Microglia. American jounal of pathology.15(4): 1021-1031. ## Motl R. 2005. Physical activity and multiple sclerosis. Journal of Multiple Sclerosis. 19(11): 450-463.##Johnson SL. 2008. The Concept of Fatigue in Multiple Sclerosis. Journal of Neuroscience Nursing . 5(1): 72-77.## Miller A, Dishon S. 2006. Health-related quality of life in multiple sclerosis: The impact of disability, gender and employment status. Quality of Life Research. 15 (2):259-71.##Contantinescu CS; Giovannoni G; Kurtzke JF; Li DKB; Sorensen PS; Ebers GC; Kesserling J, . Lassmann H; Liu C, Whitaker JN .2004. Serono Symposia International Foundation Dictionary of Multiple Sclerosis. First published in the United Kingdown by Dunitz M. London EC4P 4EE. 128:236-7.## Patel D, Castellano V, McCoy S, Blazina A, White L. 2007. For People With Mild To Moderate Multiple Sclerosis (Ms), Aerobic Exercise Can Reduce The Risk Of Coronary Artery Disease . The American Physiological Society. 22(8): 77-90.## Guzel AN, Hazar S, Erbas D. 2007. Effects of different resistance exercise protocols on nitric oxide, lipid peroxidation and creatine kinase activity in sedentary males. journal of sport science and medicine. 14(6): 417-422.## Song W, Kwak HB, Kim JH, Lawler JM. 2009. Exercise Training Modulates the Nitric Oxide Synthase Profile in Skeletal Muscle From Old Rats. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences.10(2): 125-38.## Flavell RA; Sanjabi S; Zenewicz LA, Kamanaka M. 2009. Anti-inflammatory and pro-inflammatory roles of TGF-β, IL-10, and IL-22 in immunity and autoimmunity. Current Opinion in Pharmacology. 1(9): 447-453.## Taghizadeh F, Nourian A, Nourshahi M, Srajyan A. 2014. The Effects of the Interval Aerobic Training on the Quality of Life and Physical Disability Status Scale in Patients with Multiple Sclerosis (M.S). Journal of Applied Sport Physiology. 9(17): 95-106. [Persian].##Kargarfard M, Etemadifar M, Baker P, Mehrabi M, Hayatbakhsh R. 2012. Effect of aquatic exercise training on fatigue and health-related quality of life in patients with multiple sclerosis. Archive of Physical Medicine Rehabilitation. 93(10):1701-8.## Velikonja O, Curic K, Ozura A, Jazbec SS. 2010. Influence of sports climbing and yoga on spasticity, cognitive function, mood and fatigue in patients with multiple sclerosis. Journal of Clinical Neurology Neuro surgery. 112(7):597-601.##Sangelaji B, Nabavi SM, Estebsari F, Banshi MR, Rashidian H, Jamshidi E. 2014. Effect of Combination Exercise Therapy on Walking Distance, Postural Balance, Fatigue and Quality of Life in Multiple Sclerosis Patients: A Clinical Trial Study. Iranian Red Crescent Medicine Journal. 16(6): 1-8.## Bezheh N, Soltani M, Khaleghzade H. 2015. Effects of aerobic training in water on IL-6 and IL-10 in patients with Multiple Sclerosis. Journal of Evidence Based Care. 4(11):64-72.[persian]##Williams K, Hoang D. 2009. Strength and cardiorespiratory exercise for people with multiple sclerosis. MS Australia Society. 15(3):124-138. ## Golzari Z, Shabkhiz F, Soudi S, Kordi MR, Hashemi SM. 2010. Combined exercise training reduces IFN-γ and IL-17 levels in the plasma and the supernatant of peripheral blood mononuclear cells in women with multiple sclerosis. International Immuno pharmacology. 11(5): 1-8. ## Andreasen AK, Stenager E, Dalgas U. 2011. The effect of exercise therapy on fatigue in multiple sclerosis. Multiple Sclerosis Journal. 17(9) 1041–1054.## Contantinescu CS; Giovannoni G; Kurtzke JF; Li DKB, Sorensen PS, Ebers GC; Kesserling J, Lassmann H; Liu C, Whitaker JN. 2004. Serono Symposia International Foundation Dictionary of Multiple Sclerosis. First published in the United Kingdown by Dunitz M. London EC4P 4EE. 128: 236-7.##Nunes RB, Tonetto M, Machado N, Chazan M, Heck TG, Veiga AB. 2008. Physical exercise improves plasmatic levels of IL-10, left ventricular enddiastolic pressure, and muscle lipid peroxidation in chronic heart failure rats. Journal of Apply Physiology. 104(6):1641-7.## Heesen C, Gold SM, Hartmann S, Mladek M, Reer R, Braumann KM, Wiedemann K. 2003. Endocrine and Cytokine Responses to Standardized Physical Stress in Multiple Sclerosis. Brain Behavioral Immunology. 6(1): 473-81.## Pederson B, Hoffman k. 2000. Exercise and the Immune System: Regulation, Integration, and Adaptation. Physiology Review. 80(3): 1055-81.## White LJ, Castellano V. 2008. Exercise and Brain Health-Implication for Multiple Sclerosis Part 2-Immune Factors and Stress Hormons. Journal of Sports Medicine. 75(12): 179-186.## Nunes RB, Alves JP, Kessler LP, Dal Lago P. 2013. Aerobic exercise improves the inflammatory profile correlated with cardiac remodeling and function in chronic heart failure rats. Jornal of Clinics; 68(6):876-882.## Castellano V, Darpan L, Lesley J. 2008. Cytokine responses to acute and chronic exercise in multiple sclerosis. Journal of Apply Physiology. 45(21): 1697-1702.##Niess A, Sommer M. 2000. Expression of the inducible nitric oxide synthase (iNOS) in human leukocytes: responses to running exercise. Medicine & Science in Sport & Exercise, 32(12): 1220-1225.## Zaros P, Romero PC, Bacci M, Moraes C, Zanesco A. 2009. Effect of 6-months of physical exercise on the nitrate/nitrite levels in hypertensive postmenopausal women. Journal of BMC Women Health. 17(2): 142-150.## Miller E, Mrowicka M, Malinowska K, Zolynski K, Kedziora J. 2010. Effect of the whole-body cryotherapy on a total anti oxidative statuse and activities of some anti oxidative anzymes in bllod of patients with multiple sclerosis preliminary study. Journal of Medical Investigation. 24(11): 32-39. ## Kileff J, Ashburn A. 2005. A pilot study of the effect of aerobic exercise on people with moderate disability multiple sclerosis. Clinical Rehabilitation. 142(77): 165-169.## Costello E, Raivel K, Wilson R. 2009. The Effects of a Twelve-Week Home Walking Program on Cardiovascular Parameters and Fatigue Perception of Individuals with Multiple Sclerosis: A Pilot Study. Cardiopulmonary Physical Therapy Journal. 20(1): 5-12.## Sade MR, Salesi M, Mashhadi NZ. 2015. Can aerobic exercise in Water reduce the effort of fatigue in female with multiple sclerosis: a pilot study in Yazd. International Journal of Sport Sciences. 2(1), 12-15.##
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