Department of Exercise Physiology, Faculty of Educational Sciences and Psychology, University of Mohaghegh Ardabili, Ardabil, Iran.
10.22080/jaep.2026.30489.2239
Abstract
Objectives: An increase in free radicals and oxidative stress is one of the complications of type 2 diabetes. The aim of the present research was to investigate the effect of 12 weeks of High Intensity Functional training (HIFT) and the consumption of Launaea Acanthodes on glycemic indices and antioxidant enzymes in women with type 2 diabetes. Methods: Forty type 2 diabetic women were randomly divided into 4 groups: supplement, training, training + supplement and control. Training groups performed HIFT for 12 weeks, 3 sessions per week, and each session 60 minutes. Supplement groups consumed the Launaea acanthodes at the same time as doing the exercises. Serum levels of malondialdehyde, glutathione peroxidase, superoxide dismutase and glycemic indices were measured.
Results: The level of Fasting blood glucose, hemoglobin A1C and malondialdehyde were significantly reduced in the exercise-supplement, exercise and supplement groups (p=0.001 in all three groups). The blood glucose level in the exercise-supplement group was significantly lower than the other three groups in the post-test phase (p<0.05), but the hemoglobin A1C level was only significantly lower than the supplement and control group (p<0.05). The level of insulin, glutathione peroxidase, superoxide dismutase and antioxidant capacity increased significantly in the exercise-supplement, exercise and supplement groups (p=0.001 in all three groups and for all 4 variables). The level of glutathione peroxidase and superoxide dismutase were significantly higher in the exercise-supplement group than the other three groups in the post-test phase (p<0.05). Conclusion: Both HIFT exercises and the consumption of Launaea acanthodes improved the antioxidant status and glycemic indices of women with type 2 diabetes. The improvement was greater when the two are combined compared to either of them alone.
Fathi, S. , Afroundeh, R. , & Pourrahim, A. (2025). The Effect of 12 Weeks High Intensity Fictional Training and Consumption of Launaea Acanthodes on Glycemic Indices and Antioxidant Enzymes in Women with Type 2 Diabetes. Journal of Applied Exercise Physiology, 21(42), 31-45. doi: 10.22080/jaep.2026.30489.2239
MLA
Shadi Fathi; Roghayyeh Afroundeh; Ameneh Pourrahim. "The Effect of 12 Weeks High Intensity Fictional Training and Consumption of Launaea Acanthodes on Glycemic Indices and Antioxidant Enzymes in Women with Type 2 Diabetes", Journal of Applied Exercise Physiology, 21, 42, 2025, 31-45. doi: 10.22080/jaep.2026.30489.2239
HARVARD
Fathi, S., Afroundeh, R., Pourrahim, A. (2025). 'The Effect of 12 Weeks High Intensity Fictional Training and Consumption of Launaea Acanthodes on Glycemic Indices and Antioxidant Enzymes in Women with Type 2 Diabetes', Journal of Applied Exercise Physiology, 21(42), pp. 31-45. doi: 10.22080/jaep.2026.30489.2239
CHICAGO
S. Fathi , R. Afroundeh and A. Pourrahim, "The Effect of 12 Weeks High Intensity Fictional Training and Consumption of Launaea Acanthodes on Glycemic Indices and Antioxidant Enzymes in Women with Type 2 Diabetes," Journal of Applied Exercise Physiology, 21 42 (2025): 31-45, doi: 10.22080/jaep.2026.30489.2239
VANCOUVER
Fathi, S., Afroundeh, R., Pourrahim, A. The Effect of 12 Weeks High Intensity Fictional Training and Consumption of Launaea Acanthodes on Glycemic Indices and Antioxidant Enzymes in Women with Type 2 Diabetes. Journal of Applied Exercise Physiology, 2025; 21(42): 31-45. doi: 10.22080/jaep.2026.30489.2239
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