Document Type : Research Paper
Authors
1
Department of Physical Education and Sport Sciences Neyshabur Branch, Islamic Azad University, Neyshabur, Iran
2
Department of Physical Education and Sport Sciences. Mashhad Branch, Islamic Azad University, Mashhad, Iran
3
Department of Physical Education and Sport Sciences. Neyshabur Branch, Islamic Azad University, Neyshabur, Iran.
4
Department of Physical Education and Sport Sciences. Neyshabur Branch, Islamic Azad University, Neyshabur, Iran
10.22080/jaep.2024.27146.2185
Abstract
Objectives: Resistance training is recommended for increasing muscle mass. Recently, blood flow restriction training has received attention. Therefore, the aim of the present study was to investigate the effect of 12 weeks of combined exercise training with blood flow restriction on serum levels of insulin-like growth factor-1 (IGF-1) and platelet-derived growth factor (PDGF) in inactive young women.
Methods: 45 inactive young women were selected and randomly divided into three groups: combined exercise group with BFR (n=15), traditional combined exercise (TRT) (n=15), and control group (n=15). The BFR group performed combined exercises with cuff closure and an exercise intensity of 20% of one repetition maximum; the TRT exercise group performed resistance training with 80% of 1RM 3 sessions per week for 12 weeks on consecutive days. Serum samples were collected from the subjects before and after 12 weeks of training. Serum levels of IGF-1 and PDGF were measured by ELISA. Data were analyzed using paired t-test, one-way analysis of variance, and Tukey's post hoc test at a significance level of P<0.05.
Results: Serum levels of PDGF and IGF-1 in both exercise groups increased significantly compared to the pre-test (p<0.05). Also, serum levels of PDGF and IGF-1 in the BFR and TRT groups were significantly higher than the control group (p=0.001). The levels of these indicators in the exercise groups did not show a significant difference.
Conclusion: Therefore, considering the lack of significant difference between traditional combined exercise and low-intensity combined exercise with BFR, it can be recommended to inactive women to use low-intensity exercises with BFR instead of intense exercises with similar results.
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