The Effect of Two High-Intensity Interval Training Protocols on Serum Irisin Levels in Patients with Type 2 Diabetes - A Randomized Clinical Trial

Document Type : Research Paper

Authors

1 Department of Exercise Physiology, Faculty of Physical Education and Sport Sciences, Shahid Bahonar University of kerman, Kerman, Iran.

2 Department of Sports Sciences, Faculty of Psychology and Educational Sciences, Yazd University, Yazd, Iran.

10.22080/jaep.2024.27097.2178

Abstract

Objectives: The aim of this study was to investigate the effects of high and low-volume high-intensity interval training (HIIT) on serum irisin levels and health-related anthropometric indices in men with type 2 diabetes.
Methods: In this randomized clinical trial, 34 male patients with type 2 diabetes were divided into three groups: high-volume HIIT, low-volume HIIT, and control. Both HIIT training protocols consisted of 24 sessions, performed on 3 non-consecutive days each week for 8 weeks. Serum irisin levels and anthropometric indices (LBM, WHtR, WHR, BMI and body fat percentage) were measured before and 48 hours after the final exercise session. Paired t-tests, analysis of covariance and LSD post hoc tests were used to analyze and compare the data.
 Results: A significant increase was observed in serum irisin concentrations after 8 weeks of low-volume and high-volume HIIT exercises (p<0.05). Both types of HIIT training significantly reduced the percentage of fat in men with type 2 diabetes (p<0.05). High-volume HIIT training also reduced the anthropometric index WHtR (p<0.05). After low-volume HIIT training, a significant decrease in the anthropometric indices BMI, WHtR and LBM was observed (p<0.05).
Conclusion: Both types of low-volume and high-volume HIIT training improve serum irisin levels and anthropometric indices in patients with type 2 diabetes. Therefore, considering the time savings, both types of HIIT training are recommended to improve the conditions of patients with type 2 diabetes.

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