Survey of Accuracy of Arterial CO2 Pressure Estimation From End Tidal CO2 Pressure at Three Exercise Intensities of 30, 50 and 70 Percentage of VO2max

Document Type : Research Paper

Authors

Department of Physical Education and sport Sciences, Faculty of Education and Psychology, University of Mohaghegh Ardabili, Ardabil, Iran

10.22080/jaep.2019.1828

Abstract

Background & Purpose: The aim of this study was investigation of the effect of exercise intensity on accuracy of arterial CO2 pressure estimation from end tidal CO2 pressure.
Methodology: Ten subjects were selected as samples. At first, the maximum oxygen consumption (VO2max) of each subject was obtained by performing progressive exercise protocol. Then, each subject performed three protocols with intensities of 30%, 50% and 70% of his own VO2max and duration of each exercise was 12-minute. Blood samples were taken during the rest, exercise and recovery periods, and data on respiratory gases were collected.
Results: Correlation coefficient between PaCO2 and PaCO2pre and P value in exercise with intensities of 30%, 50% and 70% of VO2max were r = 0.807, P=0.001; r=0.822, P= 0.001 and r = 0.552, P= 0.003 respectively. The percentage of estimation error was higher in the intensity of 70% of VO2max than intensities of 30% and 50% of VO2max.
Conclusion: Based on the findings of this study, it seems that the accuracy of prediction of arterial CO2 pressure from end tidal CO2 pressure is lower in high intensities exercise than low intensities exercise.

Keywords


##Ward SA. 2007. Ventilatory control in humans: constraints and limitations. Exp  physiol. 92(2): 357-366.##Moreira TS, Mulkey DK. 2015. New advances in the neural control of breathing. J Physiol. 593(5): 1065–1066.##Bruce RM. 2017. The control of ventilation during exercise: a lesson in critical thinking. Adv Physiol Educ. 41: 539 –547.##Dempsey JA, Smith CA, Blain GM, Xie A, Gong Y, Teodorescu M. 2012. Role of central/peripheral chemoreceptors and their interdependence in the pathophysiology of sleep apnea. Adv Exp Med Biol. 758: 343-9.##Poon CS. 2011. Evolving paradigms in H+ control of breathing: from homeostatic regulation to homeostatic competition. Respir physiol neurobiol. 179(2-3): 122-6.##Duffin J. 2010. The role of the central chemoreceptors: a modeling perspective. Respir physiol neurobiol. 173(3): 230-243.##Cunningham D, Robbins P, Wolff C. 1986. Integration of respiratory responses to changes in alveolar partial pressures of CO2 and O2 and in arterial pH. Am. Physiol. Soc. Bethesda, MD. 475-528.##Clement ID, Boscom DA, Conway J, Dorrington KL, O’Connor DF, Painter R, et al. 1992. An assessment of central-peripheral ventilatory chemoreflex interaction in humans. Respir physiol. 88(1-2): 87-100.##Afroundeh R, Arimitsu T, Yamanaka R, Lian CS, Yunoki T, Yano T. 2012. Effects of humoral factors on ventilation kinetics during recovery after impulse-like exercise. Acta Physiol Hung. 99(2): 185-193.##Chuang ML, Lin IF, Vintch  JRE, Tien EH. 2012. Using statistical techniques to predict dynamic arterial PCO2 in patients with COPD during maximum exercise. Respir care. 57(7): 1106-1114.##Jones NL, Robertson DG, Kane JW. 1979. Difference between end-tidal and arterial PCO2 in exercise. J Appl Physiol. 47(5): 954-960.##Van Iterson EH, and Olson TP. 2018. Use of ‘ideal’ alveolar air equations and corrected end-tidal PCO2 to estimate arterial PCO2 and physiologic dead space during exercise in patients with heart failure. Int J Cardiol. 250: 176–182.##Yosefy C, Hay E, Nasri Y, Magen E, Reisin L. 2004. End tidal carbon dioxide as a predictor of the arterial PCO2 in the emergency department setting. Emerg Med J. 21(5): 557-559.##Warner KJ, Cuschieri J, Garland B, Carlbom D, Baker D, Copass MK, et al. 2009. The utility of early end-tidal capnography in monitoring ventilation status after severe injury. J Trauma. 66(1): 26-31.##Pishbin E, Doostkhah Ahmadi G, Sharifi MD, Talebi Deloei M, Sepehri Shamloo A, Reihani H. 2015. The correlation between end-tidal carbon dioxide and arterial blood gas parameters in patients evaluated for metabolic acid-base disorders. Electronic physician. 7(3): 1095-1101.##Hassani E, Farasatkish R, Heydarpour E, Totoonchi MZ, Mahoori AR. 2009. [End tidal CO2 versus arterial CO2 monitoring in patients undergoing coronary artery bypass graft (in Persian)]. Tehran Uni Med J. 67(9): 650-654.##Yazdani R, Touhidi MH. 2012. [The correlation and level of agreement between arterial blood gas PCO2 and end-tidal CO2 in patients with chronic obstructive pulmonary disease exacerbation (in Persian)]. Razi J Med Sci. 19(103): 48-54.##Afroundeh R, Arimitsu T, Yamanaka R, Lian CS, Shirakawa K, Yunoki T, Yano T. 2014. Effect of work intensity on time delay in mediation of ventilation by arterial carbon dioxide during recovery from impulse-like exercise. Physiol. Res. 63(2): 457-463.##Zavorsky GS, Cao J, Mayo NE, Gabbay R, Murias JM. 2007. Arterial versus capillary blood gases: a meta-analysis. Respir Physiol Neurobiol. 155: 268-279.##McSwain SD, Hamel DS, Smith PB, Gentile MA, Srinivasan S, Meliones JN, et al. 2010. End-tidal and arterial carbon dioxide measurements correlate across all levels of physiologic dead space. Respir care. 55(3): 288-293.##Nicolò A, Massaroni C, Passfield L. 2017. Respiratory Frequency during Exercise: The Neglected Physiological Measure. Front Physiol. 8: 922.##Peronnet F, Meyer T, Aguilaniu B, Juneau CE, Faude O, Kindermann W. 2007. Bicarbonate infusion and pH clamp moderately reduce hyperventilation during ramp exercise in humans. J Appl Physiol. 102: 426–428.##Yamauchi H, Ito S, Sasano H, Azami T, Fisher J, Sobue K. 2011. Dependence of the gradient between arterial and end-tidal P CO2 on the fraction of inspired oxygen. Br J Anaesth. 107(4): 631-635.##Rasera CC, Gevehr PM, Domingues AM, Junior FF. 2011. The effect of body temperature on the accuracy of arterial and end-tidal carbon dioxide measurement. Measurement. 44 (1): 60–64.##DeMartini-Nolan JK, Martschinske JL, Casa DJ, Lopez RM, Stearns RL, Ganio MS, et al. 2018. Examining the influence of exercise intensity and hydration on gastrointestinal temperature in collegiate football players. J Strength Cond Res. 32(10): 2888-2896.##