عنوان مقاله [English]
Background: The previous meta-analyses haven’t provided deep understanding about the amount of the effects from training dosage and also participants’ characteristics (e.g. gender, menopause, medication use and etc.) modifying the changes in blood pressure in the hypertensive patients following to aerobic training. Therefore, meta analyses should be renewed with specific focus on this area.
Methods: Random-and fixed-effect models were used for analyzing the effect sizes were reported as difference in mean between 95% confidence intervals(CIs). For each trial subgroup (gender, menopause, medication use, exercise frequency, intensity and duration, total weekly exercise time and study duration), statistical significance was tested by using ANOVA and meta-regression performed to assess correlations between age and BP response.
Results: The overall pooled net effect of aerobic training on systolic and diastolic blood pressure was -8.72 mm Hg and -3.88 mm Hg (P=0.001), respectively.
In spite of the significant effects sizes observed for all the categories’ subgroups (in exception for SBP in low intensity training and DBP in post menopause women), different SBP reductions was only observed among the three subgroups of the “study duration” category.
Conclusion: aerobic training leads to a mild suppression in blood pressure of hypertensive patients irregardless to the moderating effects from study subgroups (age group, gender, menopause status, medication use or training dosage) with the greater reductions reported for 8 to 10 weeks of training. However; a larger and more long term CTs still remains to be done because of a very large number of limitations in the conducted trials.