اثر یک وهله تمرین تناوبی شدید بر پاسخ های سایتوکاین های پیش التهابی و ضد التهابی در بازیکنان فوتبال مرد

نوع مقاله: مقاله پژوهشی

نویسندگان

1 مرکز تحقیقات طب ورزشی، واحد نجف آباد، دانشگاه آزاد اسلامی، نجف آباد، ایران.

2 دانشکده علوم پایه، دانشگاه صنعتی قم، قم، ایران

3 آموزشکده فنی و حرفه ای سما، دانشگاه آزاد اسلامی، واحد اصفهان (خوراسگان)، اصفهان، ایران

چکیده

سابقه و هدف: فعالیت های ورزشی مختلف اثرات متفاوتی بر عوامل التهابی دارد. هدف این مطالعه، بررسی تاثیر یک وهله تمرین تناوبی شدید بر نشانگرهای پیش التهابی و ضدالتهابی در بازیکنان فوتبـال مرد بـود.
مواد و روش­ها: 19 فوتبالیسـت مـرد باشـگاهی (میـانگین سـنی 16/4±68/21سـال، قـد 6±62/180 سانتیمتر، حداکثر اکسیژن مصرفی 89/4±16/62 میلی لیتر بر کیلوگرم در دقیقه به صورت هدفمند انتخاب و به صورت تصادفی در دو گروه تجربی و کنترل تقسیم شدند. گروه تجربی در آزمون فوتبال کپنهاگ شرکت کردند و گروه کنترل تمرینات معمول را انجام دادند. قبل، بلافاصله بعد و 24 ساعت پس از انجام آزمون از کلیه آزمودنی ها خونگیری به عمل آمد. سطوح سرمی IL-6، IL-1β و TNF-α و IL-10 به روش الایزا و با استفاده از کیت های تجاری معتبر ارزیابی شدند. داده ها با استفاده از روش تحلیل واریانس با اندازه گیری های مکرر تجزیه و تحلیل شدند (05/0>p).
یافته­ا: سطوح IL-6 بلافاصله بعد (001/0=p) و 24 ساعت بعد (003/0=p) و IL-10 بلافاصله بعد (021/0=p) و 24 ساعت بعد (015/0= p) از تست افزایش معنی داری نسبت به گروه کنترل داشت. سطح TNF-α بلافاصله پس از آزمون افزایش معنی­دار یافت (001/0=p) اما 24 ساعت بعد به میزان استراحتی خود بازگشت (101/0=p). سطح IL-1β بلافاصله پس از آزمون افزایش معنی دار یافت (001/0=p) و 24 ساعت بعد به میزان کمتر از سطح استراحتی رسید (041/0=p).
نتیجه گیری: نتایج بیانگر افزایش سطوح سایتوکاین های پیش التهابی و ضدالتهابی پس از یک وهله تمرین تناوبی شدید در بازیکنان فوتبال بود بنابراین برای بدست آوردن بهترین دوره ریکاوری برای این بازیکنان به تحقیقات بیشتر نیاز است.
 

تازه های تحقیق

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کلیدواژه‌ها


عنوان مقاله [English]

The Effect of A Single Bout of Intensive Intermittent Exercise on Responses of Pro-Inflammatory and Anti-Inflammatory Cytokines in Male Soccer Players

نویسندگان [English]

  • Saeed Keshavarz 1
  • Mohammad karimi 2
  • Baharak Moradi-Kalarde 3
1 Islamic Azad University, Najafabad Branch, Najafabad, Iran
2 Faculty of Science, Qom University of Technology, Qom, Iran
3 Technical and Vocational Training College Islamic Azad University Esfahan(Khorasgan) Branch, Esfahan, Iran
چکیده [English]

Background & Purpose: Various types of exercise have different effects on inflammatory factors. The aim of this study was to survey the effect of a single bout of intensive intermittent exercise on some pro-inflammatory and anti-inflamatory markers in male soccer player.
Methodology: Ninteen male soccer players (age 21.6±4/1 years, height 180/6±6 cm and VO2max 62/1±4/8 ml.kg-1.min-1) were selected randomly and divided into two groups of experimental and control. The experimental group participated in the Copenhagen football test and control group did regular training.Blood samples collected before, immediately and 24 hours after the test. Serum levels of IL-6, IL-1β, TNF-α and IL-10 were assayed using standard commercial ELISA kits. Data were analyzed by using ANOVA with repeated measure (pResults: Serum levels of IL-6 immediately after (p=0.001) and 24 hours after (p=0.003) and IL-10 immediately after (p=0.021) and 24 hours after (p=0.015) the test increased significantly in compare to the control group. TNF-α levels increased significantly immediately after the test (p=0.001) but after 24 hours returns to the rest level (p=0.101). IL-1β levels increased significantly immediately after the test (p=0.001) and 24 hours later decreased lower than the rest levels (p=0.041).
Conclusion: The results showed levels of pro-inflammatory and anti-inflammatory cytokines increased after one bout of high intensity intermittent exercise in football players, so to get the best recovery period for these players more research is needed.

کلیدواژه‌ها [English]

  • Copenhagen test
  • inflammatory cytokines
  • anti-inflammatory cytokines
  • football players

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